Acyl bromides
Apexbio Technology LLC Umeclidinium bromide 869113-09-7 5mg
Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
Apexbio Technology LLC Umeclidinium bromide 869113-09-7 10mg
Umeclidinium bromide (CAS 869113-09-7) is a potent and long-acting antagonist of muscarinic acetylcholine receptors (mAChRs) displaying high affinity for subtypes M1 M5 with Ki values of 0 16 nM 0 15 nM 0 06 nM 0 05 nM and 0 13 nM respectively It selectively targets mAChRs without observable activity at unrelated receptors or channels such as / opioid receptors sodium channels or dopamine transporters In cell-based assays using CHO cells expressing recombinant human mAChRs umeclidinium inhibits acetylcholine-induced calcium flux with pA2 values between 9 6 and 10 6 for M1 M3 receptors In murine models it reverses acetylcholine-driven bronchoconstriction Umeclidinium bromide is broadly applied in research focused on pulmonary disease mechanisms and drug development
AdipoGen Methyltrioctadecylammonium Br
Chemical. CAS 18262-86-7. Formula C55H114BrN. MW 869.42. Synthetic. Triple chain lipid. Long chain ionophore used in anion exchange for perchlorate-selective membranes. This is as sensing material with selectivity of chloride-selective polymeric membrane electrode. Organic surfactant. Used as alkylammonium cations for the design of layered chemical sensors.
Selleck Chemical LLC Domiphen Bromide S4186-50mg
Domiphen bromide (NSC-39415) is a quaternary ammonium antiseptic with actions as a cationic surfactant
Medchemexpress LLC Tiotropium (Bromide) | 136310-93-5 | 99.9% | 472.42 | 50 MG
Tiotropium (Bromide) | 136310-93-5 | 99.9% | 472.42 | 50 MG
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | 508.49 | 250 MG
Umeclidinium bromide is a novel mAChR antagonist with high affinity for cloned human M1-M5 mAChRs. It exhibits slow functional reversibility at cloned human M3 mAChRs and at endogenous mAChR in isolated human bronchus. It also inhibits the human ether-a-go-go-related gene channel tail current in human embryonic kidney 293 cells.
- Target: mAChR
- Pathway: GPCR/G protein, neuronal signaling
- Inhibits human ether-a-go-go-related gene channel tail current
- Demonstrates slow functional reversibility at M3 mAChRs
Medchemexpress LLC Cetrimonium bromide | 57-09-0 | MFCD00011772 | 98.0% | 25 MG
Cetrimonium bromide (CTAB) is a quaternary ammonium and an orally active cationic surfactant. It exhibits toxicity and has an anticancer effect. This compound inhibits cell migration and invasion by modulating both canonical and non-canonical TGF-β signaling pathways and can also be utilized for DNA extraction.
- Cationic surfactant
- Exhibits toxicity and anticancer effect
- Inhibits cell migration and invasion
- Modulates TGF-β signaling pathways
- Can be utilized for DNA extraction
![eMolecules 7789-45-9 | Copper(II) bromide, 99% | Strem Chemicals | MFCD00010970 | 223.354 | Br2Cu | 99.000 | [Cu++].[Br-].[Br-] | 250g | 321342129](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000170901.jpg-250.jpg)
eMolecules 7789-45-9 | Copper(II) bromide, 99% | Strem Chemicals | MFCD00010970 | 223.354 | Br2Cu | 99.000 | [Cu++].[Br-].[Br-] | 250g | 321342129
Copper(II) bromide, 99% | Strem Chemicals | 7789-45-9 | MFCD00010970 | 223.354 | Br2Cu | 99.000 | [Cu++].[Br-].[Br-] | 250g | 321342129
Medchemexpress LLC N6-benzoyl-2'-deoxyadenosine monohydrate | 305808-19-9 | MFCD00009628 | ≥98.0% | 373.37 g/mol | C17H19N5O5 | 1 G
N6-Benzoyl-2'-deoxyadenosine monohydrate is a purine nucleoside analog provided as a monohydrate solid for research and diagnostic applications. It is used to study DNA duplex interactions and related biochemical assays, and is supplied at research-grade purity for laboratory use.
- High purity (≥98.0%).
- Monohydrate solid form suitable for laboratory assays.
- Used as a nucleoside analog to probe DNA duplex structure in assays.
- CAS number 305808-19-9.
- Molecular weight 373.37 g/mol.
- Available in a 1 g pack and larger sizes.
TARGETMOL CHEMICALS INC DEMECARIUM BROMIDE 50MG
Also available in 2 mg 5 mg 10 mg 25 mg 100 mg 1 mL 10 mM (in DMSO) and bulk. Please contact Fisher for quotes. Demecarium bromide (BC-48) is a potent cholinesterase inhibitorand is treatment glaucoma agent. purity: 98%
Medchemexpress LLC Demecarium Bromide | 56-94-0 | 50 MG
Demecarium Bromide is a potent cholinesterase inhibitor with an apparent affinity (Kiapp) of 0.15 μM. It is primarily used as a glaucoma agent. This product serves as an analytical standard, suitable for research and analytical applications.
- Potent cholinesterase inhibitor
- Used as a glaucoma agent
- Suitable for research and analytical applications
Medchemexpress LLC Aclidinium Bromide | 320345-99-1 | 98.96% | C₂₆H₃₀BrNO₄S₂ | 25 MG
Aclidinium Bromide is a long-acting, inhaled muscarinic antagonist with potential for research related to chronic obstructive pulmonary disease (COPD). It shows potent antagonism of human muscarinic receptors and is rapidly hydrolyzed in human plasma.
- Potent antagonism of human muscarinic receptors
- Long residence time at M3 receptors and a shorter residence time at M2 receptors
- Suggests sustained bronchodilation
- Rapid hydrolysis in human plasma
- Low systemic bioavailability and favorable safety profile in early clinical studies
![eMolecules 10031-26-2 | Iron(III) Bromide | Accela ChemBio (ASD)295.557 | Br3Fe | 98.000 | [Fe+3].[Br-].[Br-].[Br-] | 25g | 444749735](https://assets.fishersci.com/TFS-Assets/CCG/product-images/5000162575.jpg-250.jpg)
eMolecules 10031-26-2 | Iron(III) Bromide | Accela ChemBio (ASD)295.557 | Br3Fe | 98.000 | [Fe+3].[Br-].[Br-].[Br-] | 25g | 444749735
Iron(III) Bromide | Accela ChemBio (ASD) | 10031-26-2295.557 | Br3Fe | 98.000 | [Fe+3].[Br-].[Br-].[Br-] | 25g | 444749735
Medchemexpress LLC Umeclidinium bromide | 869113-09-7 | 508.49 | 100 MG
Umeclidinium bromide is a novel mAChR antagonist with an affinity (Ki) for cloned human M1-M5 mAChRs ranging from 0.05 to 0.16 nM. It inhibits the human ether-a-go-go-related gene channel tail current in a concentration-dependent manner.
- Novel mAChR antagonist
- Inhibits human ether-a-go-go-related gene channel tail current
- Shows slow functional reversibility at cloned human M3 mAChRs
- Shows slow functional reversibility at endogenous mAChR in isolated human bronchus
- For research use only